SZ-500 (Sulfasalazine 500mg)

SZ-500 Tablet is prescribed to manage a variety of inflammatory conditions involving the joints (such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis), skin (psoriasis), and the digestive tract (including ulcerative colitis and Crohn’s disease).

It should be taken with food to help reduce the risk of stomach discomfort. Consistent daily intake at the same time helps maintain its therapeutic effect. Even if you start feeling better, continue the full course as directed by your doctor. Staying well-hydrated while taking this medicine can help prevent kidney-related issues like kidney stones.

Some individuals may experience side effects such as nausea, headache, vomiting, loss of appetite, diarrhea, or general stomach discomfort. If any of these persist or become bothersome, reach out to your doctor, who may recommend steps to minimize or manage them.

Before starting SZ-500 Tablet, inform your doctor if you have any history of liver, kidney, or heart conditions. Also, share a list of any other medications you're currently using, as interactions can occur. Your doctor might also advise periodic blood tests to monitor liver and kidney function, as well as overall blood health. If you're pregnant or breastfeeding, consult your doctor before starting this medication.
 

Ulcerative colitis
Crohn’s disease
Rheumatoid arthritis
Psoriatic arthritis
Ankylosing spondylitis
Systemic lupus erythematosus (SLE)
Wilson’s disease
Type 2 diabetes mellitus

 

Most side effects are mild and temporary. However, if they persist or cause concern, consult your healthcare provider.

Common Side Effects Include:
- Diarrhea
- Stomach discomfort
- Headache
- Loss of appetite
- Nausea
- Vomiting
- Reduced sperm count (oligospermia)
 

Take this medication as prescribed by your doctor. Swallow the tablet whole with water—do not crush, chew, or break it. Always take SZ-500 Tablet with food to minimize gastrointestinal side effects.
 

SZ-500 Tablet is classified as a Disease-Modifying Anti-Rheumatic Drug (DMARD). It works by controlling an overactive immune response in autoimmune conditions and suppresses the production of inflammatory chemicals responsible for swelling and pain.

 

Alcohol : Avoid alcohol while using SZ-500 Tablet as it may increase the risk of side effects and liver damage.
Pregnancy : Studies in animals suggest no harm to the developing fetus, but human data is limited. Use under medical supervision.
Breastfeeding :There is limited data on the safety of SZ-500 Tablet during breastfeeding. The medication may pass into breast milk and affect the infant.
Driving : This medicine does not typically impair your ability to drive or operate machinery.
Kidney : If you have kidney disease, your doctor may need to adjust the dosage. Regular kidney function monitoring is recommended.
Liver : SZ-500 Tablet is not advised for individuals with liver problems. Discuss alternatives with your doctor.
Missed Dose :
If you miss a dose, take it as soon as you remember. If your next scheduled dose is near, skip the missed one. Do not take two doses at the same time to compensate.